De-QUORUM

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Quorum sensing and quorum-quenching enzymes.

To gain maximal benefit in a competitive environment, single-celled bacteria have adopted a community genetic regulatory mechanism, known as quorum sensing (QS). Many bacteria use QS signaling systems to synchronize target gene expression and coordinate biological activities among a local population. N-acylhomoserine lactones (AHLs) are one family of the well-characterized QS signals in Gram-ne...

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Quorum Sensing in Microbial Virulence

Cell-to cell communication occurs via a signaling pathway referred to as quorum sensing. There are four main types of these systems according to the chemical nature of signal molecules used by microorganisms to elicit expression of target genes in response to environmental stimuli or need of microbial communities. Type I system acts by using acyl homoserine lactones as signals to trigger the ex...

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Quorum sensing

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Extracts of Cordia gilletii de wild (Boraginaceae) quench the quorum sensing of Pseudomonas aeruginosa PAO1

AIM The fight against infectious diseases and antimicrobial resistances needs the exploration of new active compounds with new proprieties like disrupting quorum sensing (QS) mechanisms, which is a cell-to-cell communication that regulates bacterial virulence factors. In this work, leaves and root barks extracts of a Congolese medicinal plant, Cordia gilletii, were investigated for their effect...

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Synergy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Inhibiting P. aeruginosa Quorum Sensing

1 School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551 6 2 Nanyang Environment and Water Research Institute (NEWRI), Interdisciplinary Graduate School, 7 Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798 8 3 NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 Nanyang Drive, 9 Singapore 636921 10 ...

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ژورنال

عنوان ژورنال: Evidence-Based Dentistry

سال: 2004

ISSN: 1462-0049,1476-5446

DOI: 10.1038/sj.ebd.6400262